Projects

Studies Actively Recruiting Participants at HSN Sites

CTN Number	Protocol	Lead Investigators
CTN-0131	Office-Based Methadone versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment – A Randomized Pragmatic Hybrid Effectiveness/Implementation Trial This study is currently recruiting participants with opioid use disorder: ClinicalTrial.Gov study record contacts and locations. For questions about participating in this study at the Kaiser Permanente Colorado location, please email EMBOSS@kp.org or call 303-739-3666 for information.	David Fiellin and Paul Joudrey (Co-Lead Investigators) Site PI: Ingrid Binswanger, Kaiser Permanente Colorado

CTN Number

Protocol

Lead Investigators

CTN-0131

Office-Based Methadone versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment – A Randomized Pragmatic Hybrid Effectiveness/Implementation Trial

This study is currently recruiting participants with opioid use disorder: ClinicalTrial.Gov study record contacts and locations.
For questions about participating in this study at the Kaiser Permanente Colorado location, please email EMBOSS@kp.org or call 303-739-3666 for information.

David Fiellin and Paul Joudrey (Co-Lead Investigators)

Site PI: Ingrid Binswanger, Kaiser Permanente Colorado

Studies Led by Health Systems Node (HSN) Investigators

CTN Number	Protocol	Lead Investigators
CTN-0141	Health Insurance Instability and Mortality among Patients Receiving Buprenorphine Treatment for Opioid Use Disorder: Linkage of the Prescription Opioid Registry with the National Death Index	Anh Nguyen, Ingrid Binswanger, and Jason Glanz
CTN-0140	Cannabis Use in Pregnancy: Psychiatric and Substance Use Disorders	Kelly Young-Wolff
CTN-0117	The Impact of COVID-19 Pandemic on Substance Use Treatment Services	Cynthia Campbell
CTN-0113	Validating a DSM-5 Substance Use Symptom Checklist in EHR Data from a Large Primary Care Sample to Support Future Pragmatic Trials and Chronic Care Management of SUDs in Primary Care	Emily Williams and Katharine Bradley
CTN 0084-A-2	Harnessing Digital Health to Understand Clinical Trajectories of Opioid Use Disorder (D-TECT)	Cynthia Campbell and Lisa Marsch
CTN-0084-A-1	Determining the Optimal Duration of Buprenorphine Treatment to Reduce Relapse, Overdose, and Mortality	Jason Glanz, Ingrid Binswanger, Cynthia Campbell
CTN-0084	Developing a Prescription Opioid Registry across 10 Health Systems	Cynthia Campbell
CTN-0077-OT	Medical Cannabis Use Among Primary Care Patients: Using Electronic Health Records to Study Large Populations	Gwen Lapham and Katharine Bradley
CTN-0074-A-1	Primary Care Opioid Use Disorder Treatment (PROUD) Trial – Economic Analysis Study	Sean Murphy
CTN-0074	Primary Care Opioid Use Disorder Treatment (PROUD) Trial	Katharine Bradley
CTN-0072-OT	Examine Patient and System-Level Factors Associated with HEDIS AOD-IET Measure Performance across Health Systems	Constance Weisner
CTN-0065-OT	Evaluation of Drug Screening Implementation in Primary Care	Katharine Bradley
CTN-0061-OT	Kaiser Virtual Data Warehouse – Prescription Opioid Users	Cynthia Campbell

Studies with HSN Investigator Participation

CTN Number	Protocol	Lead Investigators
CTN-0139	Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care) HSN Co-Is: Katharine Bradley and Madeline Frost	Jennifer McNeely and Jane Liebschutz
CTN-0131	Office-Based Methadone versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment – A Randomized Pragmatic Hybrid Effectiveness/Implementation Trial HSN Site PI: Ingrid Binswanger	David Fiellin and Paul Joudrey
CTN-0095	Clinic-Randomized Trial of Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0) HSN Site PI: Irina Haller	Rebecca Rossom and Gavin Bart

CTN Number

Protocol

Lead Investigators

CTN-0139

Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)

HSN Co-Is: Katharine Bradley and Madeline Frost

Jennifer McNeely and Jane Liebschutz

CTN-0131

Office-Based Methadone versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment – A Randomized Pragmatic Hybrid Effectiveness/Implementation Trial

HSN Site PI: Ingrid Binswanger

David Fiellin and Paul Joudrey

CTN-0095

Clinic-Randomized Trial of Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

HSN Site PI: Irina Haller

Rebecca Rossom and Gavin Bart

NIDA Clinical Trials Network

4480 Hacienda Drive, Pleasanton, CA 94588

Contact: Monique Buffler