Scientific F​​ocus​

• ​Testing approaches to increase identification of substance use, substance use disorder, and engagement in treatment

• Testing new approaches to improve substance use disorder outcomes in medical settings 

• Developing novel measures and methods for substance use disorder research using electronic health records 

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Who we are

• The Health Systems Node (HSN) is a collaboration of investigators who conduct substance use and substance use disorder research embedded in 16 health systems across the United States, sponsored by the  National Institute on Drug Abuse (NIDA)​ Clinical Trials Network (CTN)​.​​
  

• As embedded researchers within health care systems as part of the Health Care Systems Research Network (HCSRN) or the Veterans Health Administration, Investigators in the Node have extensive expertise conducting pragmatic trials and observational comparative effectiveness research aimed at improving substance use and substance use disorder related care in medical settings. 

• The HSN is led by Dr. Cynthia Campbell  at the Kaiser Permanente Northern California Division of Research and Dr. Katharine Bradley​ at the Kaiser Permanente Washington Health Research Institute in Seattle. Dr. Constance Weisner also continues to participate as an Other Significant Contributor after transitioning from her Multiple Principal Investigator role. Learn more.

  
  

Projects and Data

• Learn more about current Health Systems Node led projects

• Leads and participates in pragmatic trials t​o test innovative approaches to improving medical care for patients with substance use and substance use disorders, such as the PROUD trial (CTN-0074) and COMPUTE 2.0 (CTN-0095).

• Conducts embedded comparative effectiveness and other health services research using innovative health systems data, such as HEDIS AOD-IET Measure Performance (CTN-0072-OT), the Prescription Opioid Registry CTN-0084), and the DTECT Study (CTN-0084-A-2)

• Conducts innovative research aimed at improving clinical measures for substance use and substance use disorders in EHRs, such as the Medical Cannabis Use Among Primary Care Patients project (CTN 0077-OT) and Validating a DSM-5 Substance Use Disorder (SUD) Symptom Checklist in EHR Data (CTN 0113)

• All projects are embedded in health systems, such as those in the Health Care System Research Network, the Veterans Health Administration, and other health care organizations.

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